Diagnostic Classification of Mental Health And Development Disorders Of Infancy and Early Childhood: DC

Author: Zero to Three
Edition: Revised
Publisher: Zero to Three
Binding: Paperback
ISBN: 0943657903

Diagnostic Classification of Mental Health And Development Disorders Of Infancy and Early Childhood: DC:0-3R

DC:0-3 was the first developmentally based system for diagnosing mental health and developmental disorders in infants and toddlers. Medical books Diagnostic Classification of Mental Health And Development Disorders Of Infancy and Early Childhood: DC. Its diagnostic categories reflected the consensus of a multidisciplinary group of experts in early childhood development and mental health. The newly revised DC:0-3R draws on empirical research and clinical practice that have occurred worldwide since 1994. DC:0-3R is designed to help mental health and other professionals. The features include: recognize mental health and developmental challenges in young children; understand how relationships and environmental factors contribute to mental health and developmental disorders; use diagnostic criteria effectively for classification and intervention; and work more effectively with parents and other professionals to develop effective treatment plans Medical books Diagnostic Classification of Mental Health and Developmental Disorders of Infancy and Early Childhood, (DC. Diagnostic Classification of Mental Health and Developmental Disorders of Infancy and Early Childhood, (DC

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Diagnostic Classification of Mental Health and Developmental Disorders of Infancy and Early Childhood, (DC

ZERO TO THREE's Diagnostic Classification of Mental Health and Developmental Disorders of Infancy and Early Childhood, Revised (DC:0?3R) enhances your ability to assess, diagnose, and treat mental health problems in infants and toddlers by identifying and describing disorders not addressed in other classification systems. Mental health professionals, physicians, nurses, early interventionists, early childhood educators, and researchers will find DC: 0-3R to be an indispensable guide to effective evaluation and treatment planning with young children and their families.

ZERO TO THREE's Diagnostic Classification of Mental Health and Developmental Disorders of Infancy and Early Childhood, Revised (DC:0?3R) enhances your ability to assess, diagnose, and treat mental health problems in infants and toddlers by identifying and describing disorders not addressed in other classification systems. Mental health professionals, physicians, nurses, early interventionists, early childhood educators, and researchers will find DC: 0-3R to be an indispensable guide to effective evaluation and treatment planning with young children and their families.

Description not available.

Medical Book Diagnostic Classification of Mental Health And Development Disorders Of Infancy and Early Childhood: DC

Its diagnostic categories reflected the consensus of a multidisciplinary group of experts in early childhood development and mental health. The newly revised DC:0-3R draws on empirical research and clinical practice that have occurred worldwide since 1994. DC:0-3R is designed to help mental health and other professionals. The features include: recognize mental health and developmental challenges in young children; understand how relationships and environmental factors contribute to mental health and developmental disorders; use diagnostic criteria effectively for classification and intervention; and work more effectively with parents and other professionals to develop effective treatment plans. DC:0-3R enhances your ability to prevent, diagnose, and treat mental health problems in the earliest years by identifying and describing disorders not addressed in other classification systems and by pointing the way to effective intervention approaches.

Cognitive Development pdf

Author: Usha Goswami
Edition: 1
Publisher: Psychology Press
Binding: Paperback
ISBN: 1841695319

Cognitive Development: The Learning Brain

Cognitive Development: The Learning Brain is a thoroughly revised and updated edition of the bestselling Cognition in Children. Medical books Cognitive Development. /EM> This full-color textbook has been re-written from the perspective of brain science and shows how new discoveries in cognitive neuroscience force us to reconsider traditional theories of cognitive development. Goswami considers the established base of cognitive developmental psychology and demonstrates how new data from brain science require a new theoretical framework based on learning. This book presents a new paradigm for teaching cognitive development, going beyond Piaget to learning and the brain.

Conceptualizing cognitive development around three core domains of human knowledge – naïve physics, naïve biology and naïve psychology – the book considers the learning mechanisms available to the infant brain Medical books Cognitive Development : A Functional Approach. by Peter J. Valletutti - Cengage Learning (1992) - Paperback - ISBN 1879105632 9781879105638

Download link for Cognitive Development in Chimpanzees

by Peter J. Valletutti - Cengage Learning (1992) - Paperback - ISBN 1879105632 9781879105638

Description not available.

Neoconstructivism: The New Science of Cognitive Development - Scott Johnson

Categories: Parent and child->Educational activities, Children's intellectual development->Parent guide. Contributors: Rae Pica - Author. Format: Paperback

Medical Book Cognitive Development

/EM> This full-color textbook has been re-written from the perspective of brain science and shows how new discoveries in cognitive neuroscience force us to reconsider traditional theories of cognitive development. Goswami considers the established base of cognitive developmental psychology and demonstrates how new data from brain science require a new theoretical framework based on learning. This book presents a new paradigm for teaching cognitive development, going beyond Piaget to learning and the brain.

Conceptualizing cognitive development around three core domains of human knowledge – naïve physics, naïve biology and naïve psychology – the book considers the learning mechanisms available to the infant brain. Each chapter explores how these mechanisms affect different aspects of cognitive development. Starting with the development of these foundational domains in infancy, Goswami goes on to consider social cognition, language acquisition, causal learning and explanation-based reasoning, and theory of mind. Later chapters explore memory, reasoning, metacognition, executive functions, reading and numbers. The final chapter analyzes the contribution of more traditional theoretical perspectives (Piaget and Vygotsky), linking these to connectionism and neuroconstructivism. The intimate links between language acquisition and symbolic systems, cognitive development and social/cultural learning form the core of the book. 

This valuable textbook is essential reading for teachers and students of developmental and cognitive psychology, as well as education, language and the learning sciences. It will also be of interest to anyone training to work with infants and children.

Cognitive Development: The Learning Brain is supported by an extensive online Cognitive Development Student Learning Program (CogDevSLP) and online Instructor Resources, both of which are free of charge to qualifying adopters and their students.

Application of Peptide-Based Prodrug Chemistry in Drug Development

Author: Arnab De
Edition: 2013
Publisher: Springer
Binding: Paperback
ISBN: 1461448743

Application of Peptide-Based Prodrug Chemistry in Drug Development (SpringerBriefs in Pharmaceutical Science & Drug Development)

Macromolecular (specifically peptide-based) drugs could potentially be highly effective medicines. Medical books Application of Peptide-Based Prodrug Chemistry in Drug Development . However they have a relatively short duration of action and variable therapeutic index. An example of such a peptide is Glucagon-like Peptide I which could potentially be used as a revolutionary drug for diabetes. This is because it stimulates insulin only when the blood glucose level is high thereby reducing the risk of hypoglycemia (a significant disadvantage of using insulin is that an insulin overdose is the single most potent cause of life-threatening hypoglycemia). However it’s short duration of action (half-life of 2 minutes in plasma) precludes its therapeutic use Medical books Application of Peptide-Based Prodrug Chemistry in Drug Development. Application of Peptide-Based Prodrug Chemistry in Drug Development

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Application of Peptide-Based Prodrug Chemistry in Drug Development

Store Search search Title, ISBN and Author Application of Peptide-Based Prodrug Chemistry in Drug Development by Arnab De Estimated delivery 3-12 business days Format Paperback Condition Brand New Suitable for chemists, biochemists, medicinal chemists, biologists and people in the medical profession (doctors), this title explains the logic behind designing peptide prodrugs, synthetic procedures and bioassays to examine the conversion of the prodrug to the drug under therapeutic conditions. Publ

Application of Peptide-Based Prodrug Chemistry in Drug Development (Paperback)

Medical Book Application of Peptide-Based Prodrug Chemistry in Drug Development

However they have a relatively short duration of action and variable therapeutic index. An example of such a peptide is Glucagon-like Peptide I which could potentially be used as a revolutionary drug for diabetes. This is because it stimulates insulin only when the blood glucose level is high thereby reducing the risk of hypoglycemia (a significant disadvantage of using insulin is that an insulin overdose is the single most potent cause of life-threatening hypoglycemia). However it’s short duration of action (half-life of 2 minutes in plasma) precludes its therapeutic use. In this volume, the use of novel therapeutics like GLP1 as an alternative to tradition insulin-based drugs in diabetes is described. Application of Peptide-Based Prodrug Chemistry in Drug Development elucidates the traditional concept of prodrugs as “specialized non-toxic protective groups used in a transient manner to alter or to eliminate certain limiting properties in the parent small molecule” (IUPAC definition). It goes on to provide insight into how prodrugs of peptides (with GLP1 as an example) could be appropriately used to extend the biological half life, broaden the therapeutic index of macromolecules and improve the pharmacodynamics of such drugs.  Author explains the logic behind designing peptide prodrugs, synthetic procedures and bioassays to examine the conversion of the prodrug to the drug under therapeutic conditions. The prodrugs described slowly convert to the parent drug at physiological conditions of 37C and pH 7.2 driven by their inherent chemical instability without the need of any enzymatic cleavage. The diketopiperazine and diketomorpholine (DKP and DMP) strategies for prodrug conversion are demonstrated in detail with special emphasis on the chemical flexibility that it offers to develop prodrugs with variable time actions. This book will be of useful to chemists, biochemists, medicinal chemists, biologists and people in the medical profession (doctors). It may be used in undergraduate classes but will certainly help post-graduate students and advanced professionals. The author is grateful to Prof. Richard DiMarchi (Standiford H. Cox Professor of Chemistry and the Linda & Jack Gill Chair in Biomolecular Sciences at Indiana University) for valuable suggestions. The foreword for the book has been written by Prof. Jean Martinez, (Legion d'Honneur awarded by the French Republic; Professor of Chemistry and Medicinal Chemistry of the University of Montpellier, France; and Chairman of European Peptide Society, 2002-2010).

Microdialysis in Drug Development

Author:
Edition: 2013
Publisher: Springer
Binding: Hardcover
ISBN: 146144814X

Microdialysis in Drug Development (AAPS Advances in the Pharmaceutical Sciences Series)

A vast number of diagnostic and therapeutic decisions are based on measuring blood concentrations of molecules, yet most biochemical and pharmacological events actually take place in the tissues. Medical books Microdialysis in Drug Development . Microdialysis is a key semi-invasive sampling technique to measure in vivo drug penetration to the target site in humans, the method being feasible in virtually every organ Medical books Microdialysis in Drug Development. A vast number of diagnostic and therapeutic decisions are based on measuring blood concentrations of molecules, yet most biochemical and pharmacological events actually take place in the tissues. Microdialysis is a key semi-invasive sampling technique to measure in vivo drug penetration to the target site in humans, the method being feasible in virtually every organ. Authored by international experts in this cutting edge field, this book will provide a comprehensive overview of microdialysis and its application for measuring drug distribution in drug development.

Download link for Microdialysis in Drug Development

A vast number of diagnostic and therapeutic decisions are based on measuring blood concentrations of molecules, yet most biochemical and pharmacological events actually take place in the tissues. Microdialysis is a key semi-invasive sampling technique to measure in vivo drug penetration to the target site in humans, the method being feasible in virtually every organ. Authored by international experts in this cutting edge field, this book will provide a comprehensive overview of microdialysis and its application for measuring drug distribution in drug development.

format hardback language english publication year 11 09 2012 series aaps advances in the pharmaceutical sciences series subject medicine subject 2 clinical medicine professional title microdialysis in drug development author muller markus editor publisher springer verlag publication date sep 11 2012 pages 338 binding hardcover edition 1 st dimensions 6 00 wx 9 00 hx 0 80 d isbn 146144814 x subject medical pharmacy description a vast number of diagnostic and therapeutic decisions are based on m

New Hardcover.

Medical Book Microdialysis in Drug Development

Microdialysis is a key semi-invasive sampling technique to measure in vivo drug penetration to the target site in humans, the method being feasible in virtually every organ. Authored by international experts in this cutting edge field, this book will provide a comprehensive overview of microdialysis and its application for measuring drug distribution in drug development.

Medical Writing in Drug Development pdf

Author: Robert J Bonk
Edition: 1
Publisher: Routledge
Binding: Paperback
ISBN: 0789004496

Medical Writing in Drug Development: A Practical Guide for Pharmaceutical Research

A guide through the maze of the pharmaceutical research and development process, Medical Writing in Drug Development fills a gap in the libraries of technical writers, college instructors, and corporate professionals associated with the pharmaceutical process. Medical books Medical Writing in Drug Development. As it discusses critical information, such as strategies and techniques pivotal to crafting documents for drug development, it also overviews drug research, document types, the roles of professional writers, and information technology. In no time at all, you will be creating persuasive technical documents, building complex facts into coherent messages, and contributing to the effective marketing of new products with promotional pieces that meet legal and ethical standards.

Medical Writing in Drug Development helps medical writers and scientific, regulatory, and marketing professionals develop a working knowledge of the technical documents crucial to successful drug research. New and seasoned professional writers alike will benefit from the book's detailed discussions of:

• using abstracts, slides, and posters to present up-to-the-minute research
  
• how patient-education materials, health-economic assessments, and electronic journals provide ongoing challenges in medical writing
  
• a dossier approach that expedites regulatory submissions for international drug development
  
• structural constraints and rhetorical approaches toward regulatory documents
  
• presenting intricate information in scientifically unbiased, yet technically convincing language
  
• the effects of electronic publishing, computer graphics, and related technology on the practice of medical writing within pharmaceutical research

Practical as a foundation text for undergraduate, graduate, and certificate programs in pharmaceutical or medical technical writing, Medical Writing in Drug Development will help you develop practical strategies for handling journal manuscripts, conference materials, and promotional pieces Medical books Medical Writing in Drug Development; A Practical Guide for Pharmaceutical Research. Categories: Drugs->Research, Medical writing, Drug Approval. Contributors: Robert J Bonk - Author. Format: Paperback

Download link for Medical Writing in Drug Development; A Practical Guide for Pharmaceutical Research

Categories: Drugs->Research, Medical writing, Drug Approval. Contributors: Robert J Bonk - Author. Format: Paperback

Categories: Drugs->Research, Medical writing, Drug Approval. Contributors: Robert J Bonk - Author. Format: Paperback

Medical Writing in Drug Development A Practical Guide for Pharmaceutical Research, ISBN-13: 9780789004499, ISBN-10: 0789004496

author robert j bonk format paperback language english publication year 01 02 1998 subject family health relationships subject 2 family health general title medical writing in drug development a practical guide for pharmaceutical research author robert j ph d bonk publisher haworth pr inc publication date feb 01 1998 pages 139 binding paperback edition 1 st dimensions 6 00 wx 8 75 hx 0 75 d isbn 0789004496 subject business economics business writing brand new paperback all orders get full acce

Medical Book Medical Writing in Drug Development

As it discusses critical information, such as strategies and techniques pivotal to crafting documents for drug development, it also overviews drug research, document types, the roles of professional writers, and information technology. In no time at all, you will be creating persuasive technical documents, building complex facts into coherent messages, and contributing to the effective marketing of new products with promotional pieces that meet legal and ethical standards.

Medical Writing in Drug Development helps medical writers and scientific, regulatory, and marketing professionals develop a working knowledge of the technical documents crucial to successful drug research. New and seasoned professional writers alike will benefit from the book's detailed discussions of:

• using abstracts, slides, and posters to present up-to-the-minute research
  
• how patient-education materials, health-economic assessments, and electronic journals provide ongoing challenges in medical writing
  
• a dossier approach that expedites regulatory submissions for international drug development
  
• structural constraints and rhetorical approaches toward regulatory documents
  
• presenting intricate information in scientifically unbiased, yet technically convincing language
  
• the effects of electronic publishing, computer graphics, and related technology on the practice of medical writing within pharmaceutical research

Practical as a foundation text for undergraduate, graduate, and certificate programs in pharmaceutical or medical technical writing, Medical Writing in Drug Development will help you develop practical strategies for handling journal manuscripts, conference materials, and promotional pieces. No other text will clarify the main aspects of the pharmaceutical research and development process while offering you insight on the key issues dominating the healthcare arena.

ADME-Enabling Technologies in Drug Design and Development pdf

Author:
Edition: 1
Publisher: Wiley
Binding: Hardcover
ISBN: 0470542780

ADME-Enabling Technologies in Drug Design and Development

A comprehensive guide to cutting-edge tools in ADME research

The last decade has seen tremendous progress in the development of analytical techniques such as mass spectrometry and molecular biology tools, resulting in important advances in drug discovery, particularly in the area of absorption, distribution, metabolism, and excretion (ADME). Medical books ADME-Enabling Technologies in Drug Design and Development. Medical books ADME-Enabling Technologies in Drug Design and Development. A comprehensive guide to cutting-edge tools in ADME researchThe last decade has seen tremendous progress in the development of analytical techniques such as mass spectrometry and molecular biology tools, resulting in important advances in drug discovery, particularly in the area of absorption, distribution, metabolism, and excretion (ADME). ADME-Enabling Technologies in Drug Design and Development focuses on the current state of the art in the field, presenting a comprehensive review of the latest tools for generating ADME data in drug discovery. It examines the broadest possible range of available technologies, giving readers the information they need to choose the right tool for a given application, a key requisite for obtaining favorable results in a timely fashion for regulatory filings. With over thirty contributed chapters by an international team of experts, the book provides:A thorough examination of current tools, covering both electronic/mechanical technologies and biologically based onesCoverage of applications for each technology, including key parameters, optimal conditions for intended results, protocols, and case studiesDetailed discussion of emerging tools and techniques, from stem cells and genetically modified animal models to imaging technologiesNumerous figures and diagrams throughout the textScientists and researchers in drug metabolism, pharmacology, medicinal chemistry, pharmaceutics, toxicology, and bioanalytical science will find ADME-Enabling Technologies in Drug Design and Development an invaluable guide to the entire drug development process, from discovery to regulatory issues.

Download link for Adme-Enabling Technologies In Drug Design And Development Ebook

A comprehensive guide to cutting-edge tools in ADME researchThe last decade has seen tremendous progress in the development of analytical techniques such as mass spectrometry and molecular biology tools, resulting in important advances in drug discovery, particularly in the area of absorption, distribution, metabolism, and excretion (ADME). ADME-Enabling Technologies in Drug Design and Development focuses on the current state of the art in the field, presenting a comprehensive review of the latest tools for generating ADME data in drug discovery. It examines the broadest possible range of avai

"A comprehensive guide to cutting-edge tools in ADME researchThe last decade has seen tremendous progress in the development of analytical techniques such as mass spectrometry and molecular biology tools, resulting in important advances in drug discovery, particularly in the area of absorption, distribution, metabolism, and excretion (ADME). ADME-Enabling Technologies in Drug Design and Development focuses on the current state of the art in the field, presenting a comprehensive review of the latest tools for generating ADME data in drug discovery. It examines the broadest possible range of ava

"A comprehensive guide to cutting-edge tools in ADME researchThe last decade has seen tremendous progress in the development of analytical techniques such as mass spectrometry and molecular biology tools, resulting in important advances in drug discovery, particularly in the area of absorption, distribution, metabolism, and excretion (ADME). ADME-Enabling Technologies in Drug Design and Development focuses on the current state of the art in the field, presenting a comprehensive review of the latest tools for generating ADME data in drug discovery. It examines the broadest possible range of ava

"A comprehensive guide to cutting-edge tools in ADME researchThe last decade has seen tremendous progress in the development of analytical techniques such as mass spectrometry and molecular biology tools, resulting in important advances in drug discovery, particularly in the area of absorption, distribution, metabolism, and excretion (ADME). ADME-Enabling Technologies in Drug Design and Development focuses on the current state of the art in the field, presenting a comprehensive review of the latest tools for generating ADME data in drug discovery. It examines the broadest possible range of ava

Medical Book ADME-Enabling Technologies in Drug Design and Development

ADME-Enabling Technologies in Drug Design and Development focuses on the current state of the art in the field, presenting a comprehensive review of the latest tools for generating ADME data in drug discovery. It examines the broadest possible range of available technologies, giving readers the information they need to choose the right tool for a given application, a key requisite for obtaining favorable results in a timely fashion for regulatory filings. With over thirty contributed chapters by an international team of experts, the book provides:

• A thorough examination of current tools, covering both electronic/mechanical technologies and biologically based ones

• Coverage of applications for each technology, including key parameters, optimal conditions for intended results, protocols, and case studies

• Detailed discussion of emerging tools and techniques, from stem cells and genetically modified animal models to imaging technologies

• Numerous figures and diagrams throughout the text

Scientists and researchers in drug metabolism, pharmacology, medicinal chemistry, pharmaceutics, toxicology, and bioanalytical science will find ADME-Enabling Technologies in Drug Design and Development an invaluable guide to the entire drug development process, from discovery to regulatory issues.

Statistical Issues in Drug Research and Development (Statistics

Author:
Edition: 1
Publisher: CRC Press
Binding: Hardcover
ISBN: 0824782909

Statistical Issues in Drug Research and Development (Statistics: A Series of Textbooks and Monographs)

Medical books Statistical Issues in Drug Research and Development (Statistics. Medical books Statistical Issues in Drug Research and Development (Statistics: a Series of Textbooks and Monographs).

Download link for Statistical Issues In Drug Research And Development Statistics: A Series Of Textbooks And Monographs

author ke peace format hardback language english publication year 11 12 1989 series statistics textbooks monographs subject medicine subject 2 clinical medicine professional title statistical issues in drug research and development author peace karl e edited by publisher marcel dekker inc publication date dec 11 1989 pages 388 binding hardcover edition 1 st dimensions 6 50 wx 9 25 hx 1 00 d isbn 0824782909 subject medical biostatistics brand new hardcover all orders get full access to our onl

*Author: Peace, Karl E./ Peace, Peace E./ Peace Karl E., Karl E. *Series Title: Statistics: Textbooks and Monographs *Binding Type: Hardcover *Number of Pages: 384 *Publication Date: 1989/12/11 *Language: English *Dimensions: 9.04 x 5.96 x 1.02 inches

Drug development is the process of finding and producing therapeutically useful pharmaceuticals turning them into safe and effective medicine and producing reliable information regarding the appropriate dosage and dosing intervals. With regulatory authorities demanding increasingly higher standards in such developments statistics has become an intrinsic and critical element in the design and conduct of drug development programmes.Statistical Issues in Drug Development presents an essential and thought provoking guide to the statistical issues and controversies involved in drug development.160T

Medical Book Statistical Issues in Drug Research and Development (Statistics

Mass Spectrometry for Drug Discovery and Drug Development pdf

Author:
Edition: 1
Publisher: Wiley
Binding: Hardcover
ISBN: 047094238X

Mass Spectrometry for Drug Discovery and Drug Development (Wiley Series on Mass Spectrometry)

Facilitates the discovery and development of new, effective therapeutics

With coverage of the latest mass spectrometry technology, this book explains how mass spectrometry can be used to enhance almost all phases of drug discovery and drug development, including new and emerging applications. Medical books Mass Spectrometry for Drug Discovery and Drug Development . The book's fifteen chapters have been written by leading pharmaceutical and analytical scientists. Their contributions are based on a thorough review of the current literature as well as their own experience developing new mass spectrometry techniques to improve the ability to discover and develop new and effective therapeutics.

Mass Spectrometry for Drug Discovery and Drug Development begins with an overview of the types of mass spectrometers that facilitate drug discovery and development. Next it covers:

• HPLC–high-resolution mass spectrometry for quantitative assays
• Mass spectrometry for siRNA
• Quantitative analysis of peptides
• Mass spectrometry analysis of biological drugs
• Applications that support medicinal chemistry investigations
• Mass spectrometry imaging and profiling

Throughout the book, detailed examples underscore the growing role of mass spectrometry throughout the drug discovery and development process Medical books Mass Spectrometry For Drug Discovery And Drug Development Korfmacher, Walter. format hardback language english publication year 12 03 2013 series wiley series on mass spectrometry subject engineering technology subject 2 industrial chemistry manufacturing title mass spectrometry for drug discovery and drug development author korfmacher walter publisher john wiley sons inc publication date jan 29 2013 pages 476 binding hardcover edition 1 st dimensions 7 25 wx 10 00 hx 1 25 d isbn 047094238 x subject science chemistry analytic description facilitates the discovery and de

Download link for Mass Spectrometry For Drug Discovery And Drug Development By Walter A. Korfm

format hardback language english publication year 12 03 2013 series wiley series on mass spectrometry subject engineering technology subject 2 industrial chemistry manufacturing title mass spectrometry for drug discovery and drug development author korfmacher walter publisher john wiley sons inc publication date jan 29 2013 pages 476 binding hardcover edition 1 st dimensions 7 25 wx 10 00 hx 1 25 d isbn 047094238 x subject science chemistry analytic description facilitates the discovery and de

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Mass Spectrometry for Drug Discovery and Drug Development Wiley 9780470942383 09780470942383

Buy Mass Spectrometry for Drug Discovery and Drug Development by and Read this Book on Kobo's Free Apps. Discover Kobo's Vast Collection of Ebooks Today - Over 3 Million Titles, Including 2 Million Free Ones!

Medical Book Mass Spectrometry for Drug Discovery and Drug Development

The book's fifteen chapters have been written by leading pharmaceutical and analytical scientists. Their contributions are based on a thorough review of the current literature as well as their own experience developing new mass spectrometry techniques to improve the ability to discover and develop new and effective therapeutics.

Mass Spectrometry for Drug Discovery and Drug Development begins with an overview of the types of mass spectrometers that facilitate drug discovery and development. Next it covers:

• HPLC–high-resolution mass spectrometry for quantitative assays
• Mass spectrometry for siRNA
• Quantitative analysis of peptides
• Mass spectrometry analysis of biological drugs
• Applications that support medicinal chemistry investigations
• Mass spectrometry imaging and profiling

Throughout the book, detailed examples underscore the growing role of mass spectrometry throughout the drug discovery and development process. In addition, images of mass spectra are provided to explain how results are interpreted. Extensive references at the end of each chapter guide readers to the primary literature in the field.

Mass Spectrometry for Drug Discovery and Drug Development is recommended for readers in pharmaceutics, including medicinal chemists, analytical chemists, and drug metabolism scientists. All readers will discover how mass spectrometry can streamline and advance new drug discovery and development efforts.