Author:
Edition: 1
Publisher: Wiley
Binding: Hardcover
ISBN: 0470542780
ADME-Enabling Technologies in Drug Design and Development
A comprehensive guide to cutting-edge tools in ADME research
The last decade has seen tremendous progress in the development of analytical techniques such as mass spectrometry and molecular biology tools, resulting in important advances in drug discovery, particularly in the area of absorption, distribution, metabolism, and excretion (ADME). Medical books ADME-Enabling Technologies in Drug Design and Development. Medical books ADME-Enabling Technologies in Drug Design and Development. A comprehensive guide to cutting-edge tools in ADME researchThe last decade has seen tremendous progress in the development of analytical techniques such as mass spectrometry and molecular biology tools, resulting in important advances in drug discovery, particularly in the area of absorption, distribution, metabolism, and excretion (ADME). ADME-Enabling Technologies in Drug Design and Development focuses on the current state of the art in the field, presenting a comprehensive review of the latest tools for generating ADME data in drug discovery. It examines the broadest possible range of available technologies, giving readers the information they need to choose the right tool for a given application, a key requisite for obtaining favorable results in a timely fashion for regulatory filings. With over thirty contributed chapters by an international team of experts, the book provides:A thorough examination of current tools, covering both electronic/mechanical technologies and biologically based onesCoverage of applications for each technology, including key parameters, optimal conditions for intended results, protocols, and case studiesDetailed discussion of emerging tools and techniques, from stem cells and genetically modified animal models to imaging technologiesNumerous figures and diagrams throughout the textScientists and researchers in drug metabolism, pharmacology, medicinal chemistry, pharmaceutics, toxicology, and bioanalytical science will find ADME-Enabling Technologies in Drug Design and Development an invaluable guide to the entire drug development process, from discovery to regulatory issues.
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Medical Book ADME-Enabling Technologies in Drug Design and Development
ADME-Enabling Technologies in Drug Design and Development focuses on the current state of the art in the field, presenting a comprehensive review of the latest tools for generating ADME data in drug discovery. It examines the broadest possible range of available technologies, giving readers the information they need to choose the right tool for a given application, a key requisite for obtaining favorable results in a timely fashion for regulatory filings. With over thirty contributed chapters by an international team of experts, the book provides:
A thorough examination of current tools, covering both electronic/mechanical technologies and biologically based ones
Coverage of applications for each technology, including key parameters, optimal conditions for intended results, protocols, and case studies
Detailed discussion of emerging tools and techniques, from stem cells and genetically modified animal models to imaging technologies
Numerous figures and diagrams throughout the text
Scientists and researchers in drug metabolism, pharmacology, medicinal chemistry, pharmaceutics, toxicology, and bioanalytical science will find ADME-Enabling Technologies in Drug Design and Development an invaluable guide to the entire drug development process, from discovery to regulatory issues.
