Author:
Edition: 1
Publisher: Wiley-Interscience
Binding: Hardcover
ISBN: 0470248475
Preclinical Development Handbook: ADME and Biopharmaceutical Properties (Pharmaceutical Development Series)
A clear, straightforward resource to guide you through preclinical drug development
Following this book's step-by-step guidance, you can successfully initiate and complete critical phases of preclinical drug development. Medical books Preclinical Development Handbook. The book serves as a basic, comprehensive reference to prioritizing and optimizing leads, dose formulation, ADME, pharmacokinetics, modeling, and regulations. This authoritative, easy-to-use resource covers all the issues that need to be considered and provides detailed instructions for current methods and techniques.
Each chapter is written by one or more leading experts in the field. These authors, representing the many disciplines involved in preclinical toxicology screening and testing, give you the tools needed to apply an effective multidisciplinary approach Medical books Preclinical Development Handbook: ADME and Biopharma..., 9780470248478. Preclinical Development Handbook: ADME and Biopharmaceutical Properties, ISBN-13: 9780470248478, ISBN-10: 0470248475
Download link for Preclinical Development Handbook: Toxicology
Preclinical Development Handbook: ADME and Biopharmaceutical Properties, ISBN-13: 9780470248478, ISBN-10: 0470248475
format hardback language english publication year 16 04 2008 series pharmaceutical development series subject medicine subject 2 clinical medicine professional title preclinical development handbook toxicology adme and biopharmaceutical properties author gad shayne cox editor armstrong duncan contributor balls michael contributor bass alan s contributor bhoga nirmala contributor publisher wiley interscience publication date apr 16 2008 pages 2432 binding hardcover edition 1 st dimensions 7 25 w
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Store Search search Title, ISBN and Author Preclinical Development Handbook: ADME and Biopharmaceutical Properties by Gad Estimated delivery 3-12 business days Format Hardcover Condition Brand New This book gives the professional pharmaceutical scientist a basic and comprehensive tool to facilitate the preclinical development process by bringing together an overview of the preclinical process and a compendium of methods and techniques that need to be considered when developing a new drug. Publi
Medical Book Preclinical Development Handbook
The book serves as a basic, comprehensive reference to prioritizing and optimizing leads, dose formulation, ADME, pharmacokinetics, modeling, and regulations. This authoritative, easy-to-use resource covers all the issues that need to be considered and provides detailed instructions for current methods and techniques.
Each chapter is written by one or more leading experts in the field. These authors, representing the many disciplines involved in preclinical toxicology screening and testing, give you the tools needed to apply an effective multidisciplinary approach. The editor has carefully reviewed all the chapters to ensure that each one is thorough, accurate, and clear.
Among the key topics covered are:
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Modeling and informatics in drug design
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Bioanalytical chemistry
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Absorption of drugs after oral administration
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Transporter interactions in the ADME pathway of drugs
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Metabolism kinetics
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Mechanisms and consequences of drug-drug interactions
Each chapter offers a full exploration of problems that may be encountered and their solutions. The authors also set forth the limitations of various methods and techniques used in determining the safety and efficacy of a drug during the preclinical stage.
This publication should be readily accessible to all pharmaceutical scientists involved in preclinical testing, enabling them to perform and document preclinical safety tests to meet all FDA requirements before clinical trials may begin.