Tuesday, July 5, 2011

Phosphodiesterases as Drug Targets pdf

Phosphodiesterases as Drug Targets



Author:
Edition: 2011
Publisher: Springer
Binding: Hardcover
ISBN: 3642179681



Phosphodiesterases as Drug Targets (Handbook of Experimental Pharmacology)


Cyclic nucleotide phosphodiesterases (PDEs) are promising targets for pharmacological intervention. Medical books Phosphodiesterases as Drug Targets . Medical books Phosphodiesterases As Drug Targets: Vol 204 Francis, Sharron H. (editor)/ Conti,. format hardback language english publication year 31 07 2011 series handbook of experimental pharmacology subject mathematics sciences subject 2 life sciences general title phosphodiesterases as drug targets vol 204 author francis sharron h editor conti marco editor houslay miles d editor publisher springer verlag publication date sep 23 2011 pages 519 binding hardcover edition 1 st dimensions 6 25 wx 9 25 hx 1 00 d isbn 3642179681 subject medical pharmacology description cyclic nucleotide pho

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format hardback language english publication year 31 07 2011 series handbook of experimental pharmacology subject mathematics sciences subject 2 life sciences general title phosphodiesterases as drug targets vol 204 author francis sharron h editor conti marco editor houslay miles d editor publisher springer verlag publication date sep 23 2011 pages 519 binding hardcover edition 1 st dimensions 6 25 wx 9 25 hx 1 00 d isbn 3642179681 subject medical pharmacology description cyclic nucleotide pho

Phosphodiesterases as Drug Targets (Handbook of Experimental Pharmacology), ISBN-13: 9783642179686, ISBN-10: 3642179681

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Phosphodiesterases As Drug Targets SPRIV 9783642179686 09783642179686



Medical Book Phosphodiesterases as Drug Targets



Multiple PDE genes, isoform diversity, selective expression and compartmentation of the isoforms, and an array of conformations of PDE proteins are properties that challenge development of drugs that selectively target this class of enzymes. Novel characteristics of PDEs are viewed as unique opportunities to increase specificity and selectivity when designing novel compounds for certain therapeutic indications. This chapter provides a summary of the major concepts related to the design and use of PDE inhibitors.

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